CHEMICAL EFFECTS in BIOLOGICAL SYSTEMS

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Experiment ID Investigator's Name All Balshaw, David Boorman, Gary Borlak, Jurgan Devereux, Theodora Heinloth, Alexandra Investigator, Anonymous Johnson, J. Kaufmann, William Kleeberger, Steven Kramer, Jeffery Natsoulis, Georges Paules, Richard Pettit, Syril Pettit, Syril Tennant, Raymond Trempus, Carol Williams, Robert Experiment Title All A 1-, 3- & 7-Day Oral (Gavage) Gene Array Toxicity Study in Male SD Rats on Methapyrilene. Acetaminophen: Gene expression profiling of rat livers reveals indicators of potential adverse effects of acetaminophen Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling Application of 1,2-dichlorobenzene to F344/N rats via oral gavage to evaluate acute toxicity Application of 1,4-dichlorobenzene to F344/N rats via oral gavage to evaluate acute toxicity Application of N-nitrosomorpholine to F344/N rats via oral gavage to evaluate acute toxicity Application of bromobenzene to F344/N rats via oral gavage to evaluate acute toxicity Application of diquat dibromide to F344/N rats via intraperitoneal administration to evaluate acute toxicity Application of galactosamine-HCl to F344/N rats via intraperitoneal administration to evaluate acute toxicity Application of monocrotaline to F344/N rats via oral gavage to evaluate acute toxicity Application of thioacetamide to F344/N rats via oral gavage to evaluate acute toxicity Characterization of gene expression in hematopoetic stem cells and forebrain from recombinant inbred mouse strains Clofibrate: One, three and seven day oral gene array and toxicity study in the male Sprague Dawley rats performed at Abbott Laboratories Clofibrate: One, three and seven day oral (gavage) gene array and toxicity stude of clofibrate in the male Sprague Dawley rat performed at GSK. Control Base Line Study - RAE230A Control Base Line Study - RAE230_2 Control Base Line Study - RGU34A Evaluation of carcinogenesis with eugenol and methyleugenol via oral gavage in B6C3F1 mice Evaluation of carcinogenesis with oxazepam, o-nitrotoluene, p-nitrotoluene and acetaminophen via feed in male and female B6C3F1 mice Evaluation of variation in the hepatic gene expression in individual male Fischer rats Gene Expression of the Left and Median Liver Lobes of Male F344/N Rats Following Exposure to Acetaminophen Gene expression library of hepatotoxicants in rat liver deposited by Johnson & Johnson Gene expression profiling of Nrf2-mediated protection against oxidative injury HESI_Cisplatin_SD HESI_Gentamicin Iconix Hepatotoxicants Methapyrilene: One, three and seven day oral gene array and toxicity study in the male Sprague Dawley rats performed at Abbott Laboratories Molecular mechanism investigation of phenobarbital-induced serum cholesterol elevation in rat livers by microarray analysis Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance Species All C. elegans Human Mouse Rat Rat,Rat Image Processing Software All Microarray Affy-MAS 5.0 Affymetrix Agilent ArraySuite CEBS One Channel CEBS Two Channel GenePix Molecularware QuantArray Spot On Unsupported    Search Experiments

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