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Study Information
Study Attribute Value
CEBS Accession Number: 002-01045-0018-0000-1
Chemical Name: 1,2-Dibromoethane
CASRN: 106-93-4
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 738945_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 04/17/89 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.4447
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 13.75 ± 1.58 0.0000
Test Chemical 1,2-Dibromoethane 
37.5       
 8 2.00 ± 0.76 0.3865
  
75         
 8 1.00 ± 0.65 0.8026
  
150         
 8 2.00 ± 0.38 0.3865
Vehicle Control No Stressor 
 0         
 7 1.71 ± 0.68 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 01/05/93 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.8809
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
25         
 8 27.50 ± 2.03 0.0000
Test Chemical 1,2-Dibromoethane 
37.5       
 8 1.00 ± 0.53 0.6313
  
75         
 8 0.75 ± 0.53 0.7614
  
150         
 8 0.50 ± 0.33 0.8726
Vehicle Control No Stressor 
 0         
 8 1.25 ± 0.37 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed