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Study Information
Study Attribute Value
CEBS Accession Number: 002-01065-0014-0000-9
Chemical Name: 1,2-Propylene oxide
CASRN: 75-56-9
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 669217_SCE
Study Result: Positive (Nonstandard Protocol)


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 05/24/89 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Phosphate Buffered Saline 
 0         
 4 4.68 ± 0.918
Test Chemical 1,2-Propylene oxide 
75         
 3 4.93 ± 0.972
  
150         
 4 4.95 ± 0.439
  
300         
 4 11.35 ± 1.496
Positive Control Mitomycin-C 
 0.5       
 4 7.46 ± 0.508


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed