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Study Information
Study Attribute Value
CEBS Accession Number: 002-01076-0013-0000-0
Chemical Name: 1,3-Dichloropropene (Telone II)
CASRN: 542-75-6
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 208737_SCE
Study Result: Negative (Nonstandard Protocol)


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 01/13/87 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 6.28 ± 0.860
Test Chemical 1,3-Dichloropropene (Telone II) 
50         
 4 5.15 ± 0.396
  
100         
 4 4.92 ± 0.462
  
200         
 3 6.74 ± 0.264
Positive Control Dimethylbenzanthracene 
2.5       
 4 9.29 ± 0.314


Summary of Sister Chromatid Exchange Data (Trial 2)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 02/22/88 42 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  42 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 6.21 ± 1.911
Test Chemical 1,3-Dichloropropene (Telone II) 
50         
 4 4.23 ± 1.034
  
100         
 4 4.30 ± 0.389
  
200         
 4 3.79 ± 0.489
Positive Control Dimethylbenzanthracene 
2.5       
 4 7.97 ± 1.391


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed