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Study Information
Study Attribute Value
CEBS Accession Number: 002-01142-0001-0000-1
Chemical Name: 11-Aminoundecanoic acid
CASRN: 2432-99-7
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 084118_SCE
Study Result: Positive

Study Result: Positive
Activation Trial Trial Call
No Activation  1  Positive 
Induced Rat Liver S9  1_S9  Negative 

Trial #: 1    Activation: No Activation    Date: 12/03/1981    Trial Call: Positive   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Water 
0         
 50 1040 383 0.368 7.66 25.8 0.000
Test Chemical 11-Aminoundecanoic acid 
500         
 50 1040 474 0.456 9.48 25.8 23.760 
750         
 50 1040 597 0.574 11.94 25.8 55.875 
1000         
 50 1028 583 0.567 11.66 25.8 53.996
Positive Control Mitomycin-C 
 0.005     
 50 1046 1376 1.315 27.52 25.8 257.208
Trend: 7.495        
Probability: 0.000        

Trial #: 1_S9    Activation: Induced Rat Liver S9    Date: 12/03/1981    Trial Call: Negative   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Water 
0         
 50 1031 392 0.380 7.84 25.5 0.000
Test Chemical 11-Aminoundecanoic acid 
500         
 50 1028 379 0.369 7.58 25.5 -3.034 
750         
 50 1037 370 0.357 7.40 25.5 -6.158 
1000         
 50 1032 408 0.395 8.16 25.5 3.981
Positive Control Cyclophosphamide 
1.5       
 50 1038 1088 1.048 21.76 25.5 175.679
Trend: 0.312        
Probability: 0.377