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Study Information
Study Attribute Value
CEBS Accession Number: 002-01142-0011-0000-2
Chemical Name: 11-Aminoundecanoic acid
CASRN: 2432-99-7
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 379527_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 08/07/89 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.3481
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
50         
 8 5.50 ± 1.40 0.0004
Test Chemical 11-Aminoundecanoic acid 
1250         
 8 1.25 ± 0.53 0.5000
  
2500         
 8 1.75 ± 0.59 0.2804
  
5000         
 8 1.50 ± 0.50 0.3807
Vehicle Control No Stressor 
 0         
 8 1.25 ± 0.37 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 09/29/92 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.0001
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
25         
 8 16.75 ± 1.73 0.0000
Test Chemical 11-Aminoundecanoic acid 
375         
 8 2.50 ± 0.73 0.7372
  
750         
 8 1.75 ± 0.70 0.9129
  
1500         
 8 7.75 ± 2.63 0.0026
Vehicle Control No Stressor 
 0         
 8 3.25 ± 0.53 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 03/30/93 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.7896
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
25         
 8 34.00 ± 2.62 0.0000
Test Chemical 11-Aminoundecanoic acid 
750         
 8 2.00 ± 0.85 0.7570
  
1000         
 8 3.50 ± 0.91 0.2711
  
1500         
 8 1.50 ± 0.73 0.8899
Vehicle Control No Stressor 
 0         
 8 2.75 ± 0.75 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed