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Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-01142-0011-0000-2 |
Chemical Name: | 11-Aminoundecanoic acid |
CASRN: | 2432-99-7 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | 379527_CA |
Study Result: | Negative |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 08/07/89 | 17 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 17 hour | 0.3481 |
Test Group | Dose (mg/kg) |
n | Percent Cells w/ Aberrations (Mean ± SEM) |
Pairwise P | |
---|---|---|---|---|---|
Positive Control | Dimethylbenzanthracene | 50 |
8 | 5.50 ± 1.40 | 0.0004 |
Test Chemical | 11-Aminoundecanoic acid | 1250 |
8 | 1.25 ± 0.53 | 0.5000 |
2500 |
8 | 1.75 ± 0.59 | 0.2804 | ||
5000 |
8 | 1.50 ± 0.50 | 0.3807 | ||
Vehicle Control | No Stressor | 0 |
8 | 1.25 ± 0.37 | 0.0000 |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 09/29/92 | 36 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 36 hour | 0.0001 |
Test Group | Dose (mg/kg) |
n | Percent Cells w/ Aberrations (Mean ± SEM) |
Pairwise P | |
---|---|---|---|---|---|
Positive Control | Dimethylbenzanthracene | 25 |
8 | 16.75 ± 1.73 | 0.0000 |
Test Chemical | 11-Aminoundecanoic acid | 375 |
8 | 2.50 ± 0.73 | 0.7372 |
750 |
8 | 1.75 ± 0.70 | 0.9129 | ||
1500 |
8 | 7.75 ± 2.63 | 0.0026 | ||
Vehicle Control | No Stressor | 0 |
8 | 3.25 ± 0.53 | 0.0000 |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 03/30/93 | 36 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 36 hour | 0.7896 |
Test Group | Dose (mg/kg) |
n | Percent Cells w/ Aberrations (Mean ± SEM) |
Pairwise P | |
---|---|---|---|---|---|
Positive Control | Dimethylbenzanthracene | 25 |
8 | 34.00 ± 2.62 | 0.0000 |
Test Chemical | 11-Aminoundecanoic acid | 750 |
8 | 2.00 ± 0.85 | 0.7570 |
1000 |
8 | 3.50 ± 0.91 | 0.2711 | ||
1500 |
8 | 1.50 ± 0.73 | 0.8899 | ||
Vehicle Control | No Stressor | 0 |
8 | 2.75 ± 0.75 | 0.0000 |