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Study Information
Study Attribute Value
CEBS Accession Number: 002-01179-0021-0000-3
Chemical Name: 2,3,7,8-Tetrachlorodibenzo-p-dioxin
CASRN: 1746-01-6
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 163229_SCE
Study Result: Not a Valid Test


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 02/03/88 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(ug/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 6.64 ± 0.844
Test Chemical 2,3,7,8-Tetrachlorodibenzo-p-dioxin 
250         
 4 4.48 ± 0.569
  
500         
 4 4.86 ± 0.808
  
1000         
 4 4.64 ± 0.538
Positive Control Dimethylbenzanthracene 
2.5       
 4 5.17 ± 0.287


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed