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Study Information
Study Attribute Value
CEBS Accession Number: 002-01190-0010-0000-4
Chemical Name: 2,3-Dichloropropylene
CASRN: 78-88-6
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 313269_SCE
Study Result: Negative (Nonstandard Protocol)


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 11/25/85 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 5.09 ± 0.349
Test Chemical 2,3-Dichloropropylene 
22.5       
 4 6.23 ± 0.412
  
45         
 4 5.31 ± 0.518
  
90         
 4 5.92 ± 0.555
Positive Control Dimethylbenzanthracene 
2.5       
 4 10.74 ± 1.345


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed