Genetic Toxicology - Rodent Cytogenetics

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Study Information
Study Attribute	Value
CEBS Accession Number:	002-01254-0018-0000-3
Chemical Name:	2,6-Toluenediamine dihydrochloride (2,6-diaminotoluene dihydrochloride)
CASRN:	15481-70-6
NTP Study Type:	Genetic Toxicology - Rodent Cytogenetics
NTP Study ID:	337746_SCE
Study Result:	Negative (Nonstandard Protocol)

View Study Details | View Protocol | Download To Excel

Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.

Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type	Start Date	Sample Time (h)	Species	Sex	Strain	Tissue	Protocol	Trend Test P
SCE	07/16/86	23	Mouse	Male	B6C3F1	Bone Marrow	IP/IJ x 1, 23 hour

		Dose (mg/kg)	n	SCE / Cell (Mean ± SEM)
Vehicle Control	Phosphate Buffered Saline	0	4	4.93 ± 0.233
Test Chemical	2,6-Toluenediamine dihydrochloride (2,6-diaminotoluene dihydrochloride)	25	4	5.15 ± 0.258
		50	4	5.02 ± 0.342
		100	4	3.75 ± 0.234
Positive Control	Mitomycin-C	0.5	4	10.01 ± 1.745

Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed