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Study Information
Study Attribute Value
CEBS Accession Number: 002-01265-0005-0000-1
Chemical Name: 2-Acetylaminofluorene
CASRN: 53-96-3
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 172752_SCE
Study Result: Positive


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 07/28/83 17 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  17 hour
  Dose
(mg/kg)
n SCE / Cell
(Mean ± SEM)
Pairwise P
Vehicle Control Corn Oil
 0         
4 4.54 ± 0.421
Test Chemical 2-Acetylaminofluorene
250         
4 4.66 ± 0.203
 
500         
4 10.97 ± 1.141
 
1000         
4 15.16 ± 0.922


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed