COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
Study Information
Study Attribute Value
CEBS Accession Number: 002-01311-0012-0000-1
Chemical Name: 2-Chloroethanol (ethylene chlorohydrin)
CASRN: 107-07-3
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 208472_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 03/24/86 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.7157
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
1         
 8 3.50 ± 0.91 0.0035
Test Chemical 2-Chloroethanol (ethylene chlorohydrin) 
25         
 8 1.75 ± 0.59 0.1015
  
50         
 8 0.50 ± 0.33 0.6731
  
100         
 8 0.75 ± 0.37 0.5000
Vehicle Control No Stressor 
 0         
 8 0.75 ± 0.37 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 10/27/87 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.1355
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
1         
 8 10.25 ± 1.91 0.0000
Test Chemical 2-Chloroethanol (ethylene chlorohydrin) 
25         
 8 1.00 ± 0.53 0.7378
  
50         
 8 1.00 ± 0.38 0.7378
  
100         
 8 2.25 ± 0.70 0.2171
Vehicle Control No Stressor 
 0         
 8 1.50 ± 0.50 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed