Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-01314-0015-0000-7 |
Chemical Name: | 2-Chloromethylpyridine hydrochloride |
CASRN: | 6959-47-3 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | 145263_CA |
Study Result: | Negative (Nonstandard Protocol) |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 07/10/85 | 17 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 17 hour | 0.0408 |
Test Group | Dose (mg/kg) | n | Percent Cells w/ Aberrations (Mean ± SEM) | Pairwise P | |
---|---|---|---|---|---|
Positive Control | Mitomycin-C | 0.5 | 8 | 3.00 ± 0.53 | 0.0035 |
Test Chemical | 2-Chloromethylpyridine hydrochloride | 75 | 8 | 0.50 ± 0.33 | 0.5000 |
150 | 8 | 0.75 ± 0.37 | 0.3269 | ||
300 | 8 | 1.50 ± 1.05 | 0.0776 | ||
Vehicle Control | No Stressor | 0 | 8 | 0.50 ± 0.33 | 0.0000 |
Footnotes: IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed
INHAL: Inhalation
n: Number of animals analyzed