Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit  cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Study Information
Study Attribute Value
CEBS Accession Number: 002-01391-0011-0000-8
Chemical Name: 3,3'-Dimethylbenzidine dihydrochloride
CASRN: 612-82-8
NTP Study Type: Genetic Toxicology - Drosophila Germ Cell Mutagenicity
NTP Study ID: 475156_RT
Study Result: Negative


You may also view: Sex-Linked Recessive Lethal Data for this study.


Drosophila Reciprocal Translocations Study Details
Route of Exposure Dose
ppm		 Solvent No. RTs / No. tests per sperm batch (in days of storage *) Total No. of Translocations Translocation
Frequency
(%)
0-3 3-7 7-10 10-14 14-17 17-20
Test Chemical 
14000         
 Distilled Water 0/857 0/820 0/836 0/833 0/819 0/629 0/4794 0.00
 
Days of Storage: The number of days sperm were stored in the female before testing.