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Study Information
Study Attribute Value
CEBS Accession Number: 002-01515-0014-0000-9
Chemical Name: 4-Nitro-o-phenylenediamine
CASRN: 99-56-9
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 704945_CA
Study Result: Negative (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 06/28/84 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.5652
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
200         
 8 18.75 ± 3.21 0.0000
Test Chemical 4-Nitro-o-phenylenediamine 
250         
 8 1.50 ± 0.50 0.7051
  
500         
 8 1.50 ± 0.73 0.7051
  
1000         
 8 1.75 ± 0.59 0.6028
Vehicle Control No Stressor 
 0         
 8 2.00 ± 1.25 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed