Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-01530-0004-0000-5 |
Chemical Name: | 5-(4-Nitrophenyl)-2,4-pentadien-1-al (NPPD) |
CASRN: | 2608-48-2 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | A84710_CA |
Study Result: | Negative (Nonstandard Protocol) |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 09/19/85 | 17 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 17 hour | 0.3537 |
Test Group | Dose (mg/kg) | n | Percent Cells w/ Aberrations (Mean ± SEM) | Pairwise P | |
---|---|---|---|---|---|
Positive Control | Dimethylbenzanthracene | 100 | 8 | 9.25 ± 2.10 | 0.0000 |
Test Chemical | 5-(4-Nitrophenyl)-2,4-pentadien-1-al (NPPD) | 100 | 8 | 3.50 ± 0.73 | 0.0608 |
200 | 8 | 4.00 ± 1.20 | 0.0284 | ||
400 | 8 | 2.50 ± 0.50 | 0.2310 | ||
Vehicle Control | No Stressor | 0 | 8 | 1.75 ± 0.59 | 0.0000 |
Footnotes: IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed
INHAL: Inhalation
n: Number of animals analyzed