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Study Information
Study Attribute Value
CEBS Accession Number: 002-01634-0010-0000-7
Chemical Name: Allyl isovalerate
CASRN: 2835-39-4
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 070779_SCE
Study Result: Positive (Nonstandard Protocol)


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 09/12/88 42 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  42 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 4.23 ± 0.271
Test Chemical Allyl isovalerate 
37.5       
 4 4.77 ± 0.239
  
75         
 4 5.03 ± 0.324
  
150         
 4 5.15 ± 0.532
Positive Control Dimethylbenzanthracene 
2.5       
 4 12.14 ± 0.381


Summary of Sister Chromatid Exchange Data (Trial 2)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 03/14/89 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 5.49 ± 0.365
Test Chemical Allyl isovalerate 
37.5       
 4 5.59 ± 0.419
  
75         
 4 5.58 ± 0.283
  
150         
 4 5.95 ± 0.638
Positive Control Dimethylbenzanthracene 
2.5       
 4 12.81 ± 1.140


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed