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Study Information
Study Attribute Value
CEBS Accession Number: 002-01634-0011-0000-8
Chemical Name: Allyl isovalerate
CASRN: 2835-39-4
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 070779_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 03/08/89 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.0673
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
25         
 8 15.50 ± 2.38 0.0000
Test Chemical Allyl isovalerate 
37.5       
 8 4.25 ± 1.53 0.0100
  
75         
 8 2.50 ± 1.18 0.1562
  
150         
 8 4.00 ± 1.60 0.0153
Vehicle Control No Stressor 
 0         
 8 1.50 ± 0.50 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 03/22/89 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.2123
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 13.00 ± 0.85 0.0000
Test Chemical Allyl isovalerate 
37.5       
 8 1.00 ± 0.38 0.7378
  
75         
 8 1.00 ± 0.53 0.7378
  
150         
 8 2.00 ± 1.25 0.2949
Vehicle Control No Stressor 
 0         
 8 1.50 ± 0.50 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed