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Study Information
Study Attribute Value
CEBS Accession Number: 002-01688-0001-0000-6
Chemical Name: Benzaldehyde
CASRN: 100-52-7
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 081912_SCE
Study Result: Positive

Study Result: Positive
Activation Trial Trial Call
No Activation  1  Positive 
Induced Rat Liver S9  1_S9  Weakly Positive 

Trial #: 1    Activation: No Activation    Date: 06/10/1981    Trial Call: Positive   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Dimethyl Sulfoxide 
0         
 50 1045 459 0.439 9.18 26.0 0.000
Test Chemical Benzaldehyde 
5         
 50 1045 481 0.460 9.62 26.0 4.793 
16         
 50 1045 512 0.490 10.24 26.0 11.547 
50         
 50 1044 567 0.543 11.34 26.0 23.648 
160         
 50 1034 689 0.666 13.78 26.0 51.706
Positive Control Triethylenemelamine 
 0.015     
 50 1044 1781 1.706 35.62 26.0 288.389
Trend: 7.589        
Probability: 0.000        

Trial #: 1_S9    Activation: Induced Rat Liver S9    Date: 06/10/1981    Trial Call: Weakly Positive   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Dimethyl Sulfoxide 
0         
 50 1048 431 0.411 8.62 26.0 0.000
Test Chemical Benzaldehyde 
160         
 50 1049 469 0.447 9.38 26.0 8.713 
500         
 50 1047 489 0.467 9.78 26.0 13.565 
1600         
 50 1050 566 0.539 11.32 26.0 31.072
Positive Control Cyclophosphamide 
1         
 50 1049 1165 1.111 23.30 26.0 170.044
Trend: 4.283        
Probability: 0.000