Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-01690-0019-0000-8 |
Chemical Name: | Benzene |
CASRN: | 71-43-2 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | 867104_SCE |
Study Result: | Positive |
Table Instructions and Notes:
Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.
Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|---|
SCE | 02/18/87 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
---|---|---|---|---|---|
Vehicle Control | Corn Oil | 0 | 4 | 4.02 ± 0.499 | |
Test Chemical | Benzene | 950 | 4 | 5.95 ± 0.458 | |
1900 | 4 | 5.64 ± 0.870 | |||
3800 | 4 | 8.36 ± 0.322 | |||
Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 5.81 ± 0.420 |
Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|---|
SCE | 01/12/89 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
---|---|---|---|---|---|
Vehicle Control | Corn Oil | 0 | 4 | 5.48 ± 0.575 | |
Test Chemical | Benzene | 950 | 4 | 9.47 ± 0.516 | |
1900 | 4 | 8.77 ± 1.588 | |||
3800 | 3 | 11.90 ± 2.904 | |||
Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 9.33 ± 0.593 |
Footnotes: IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed