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Study Information
Study Attribute Value
CEBS Accession Number: 002-01698-0011-0000-8
Chemical Name: Benzo(a)pyrene
CASRN: 50-32-8
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: A76267_CA
Study Result: Positive (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 05/09/84 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0003
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Test Chemical Benzo(a)pyrene 
62.5       
 8 0.75 ± 0.37 0.1580
  
125         
 8 1.00 ± 0.76 0.0892
  
250         
 8 2.75 ± 0.65 0.0018
Vehicle Control No Stressor 
 0         
 8 0.25 ± 0.25 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed