| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-01712-0021-0000-6 |
| Chemical Name: | Benzyl acetate |
| CASRN: | 140-11-4 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 500814_SCE |
| Study Result: | Negative |
Table Instructions and Notes:
Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 12/10/90 | 42 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 42 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Corn Oil | 0 | 4 | 4.65 ± 0.799 | |
| Test Chemical | Benzyl acetate | 325 | 4 | 4.10 ± 0.709 | |
650 | 4 | 6.59 ± 1.687 | |||
1300 | 4 | 4.14 ± 0.484 | |||
| Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 8.61 ± 0.696 | |
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 02/18/87 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Corn Oil | 0 | 4 | 4.02 ± 0.499 | |
| Test Chemical | Benzyl acetate | 425 | 4 | 3.89 ± 0.763 | |
850 | 4 | 4.64 ± 1.171 | |||
1700 | 3 | 4.01 ± 0.194 | |||
| Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 5.81 ± 0.420 | |
Footnotes: IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed