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Study Information
Study Attribute Value
CEBS Accession Number: 002-01744-0002-0000-0
Chemical Name: Bromoethane (ethyl bromide)
CASRN: 74-96-4
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 496296_CA
Study Result: Negative

Study Result: Negative
Activation Trial Trial Call
No Activation  1  Negative 
Induced Rat Liver S9  1_S9  Negative 

Trial #:1   Activation: No Activation    Date: 03/14/1985    Harvest Time: 10.5 hour(s)   Trial Call: Negative   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Dimethyl Sulfoxide 
0         
 100 1 0.010 1.0 0 0.000 0.0 1 0.010 1.0 0 0.000 0.0
Test Chemical: Bromoethane (ethyl bromide) 
100         
 100 4 0.040 4.0 1 0.010 1.0 3 0.030 3.0 0 0.000 0.0 
300         
 100 2 0.020 2.0 0 0.000 0.0 2 0.020 2.0 0 0.000 0.0 
1000         
 100 4 0.040 4.0 0 0.000 0.0 4 0.040 4.0 0 0.000 0.0
Positive Control: Mitomycin-C 
5         
 50 36 0.720 36.0 15 0.300 24.0 11 0.220 18.0 10 0.200 1.0
Trend: 0.971 -0.439 1.157  
Probability: 0.166 0.670 0.124  


Trial #:1_S9   Activation: Induced Rat Liver S9    Date: 03/14/1985    Harvest Time: 12 hour(s)   Trial Call: Negative   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Dimethyl Sulfoxide 
0         
 100 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
Test Chemical: Bromoethane (ethyl bromide) 
100         
 100 1 0.010 1.0 0 0.000 0.0 1 0.010 1.0 0 0.000 0.0 
300         
 100 4 0.040 3.0 1 0.010 1.0 3 0.030 2.0 0 0.000 0.0 
1000         
 100 3 0.030 1.0 0 0.000 0.0 3 0.030 1.0 0 0.000 0.0
Positive Control: Cyclophosphamide 
50         
 50 55 1.100 54.0 21 0.420 38.0 24 0.480 30.0 10 0.200 1.0
Trend: 0.978 0.419 0.882  
Probability: 0.164 0.338 0.189