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Study Information
Study Attribute Value
CEBS Accession Number: 002-01750-0019-0000-5
Chemical Name: Butyl benzyl phthalate
CASRN: 85-68-7
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 336452_SCE
Study Result: Positive


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 08/11/87 42 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  42 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 4.79 ± 0.211
Test Chemical Butyl benzyl phthalate 
1250         
 4 5.73 ± 0.198
  
2500         
 4 4.56 ± 0.259
  
5000         
 4 5.99 ± 0.207


Summary of Sister Chromatid Exchange Data (Trial 2)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 02/17/88 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 5.98 ± 0.439
Test Chemical Butyl benzyl phthalate 
1250         
 4 6.62 ± 0.853
  
2500         
 4 9.23 ± 0.856
  
5000         
 5 6.99 ± 0.736
Positive Control Dimethylbenzanthracene 
2.5       
 4 9.38 ± 0.322


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed