COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
Study Information
Study Attribute Value
CEBS Accession Number: 002-01763-0013-0000-3
Chemical Name: C.I. Acid orange 10
CASRN: 1936-15-8
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 295893_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 12/01/86 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.1639
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
 0.5       
 8 13.75 ± 1.53 0.0000
Test Chemical C.I. Acid orange 10 
550         
 8 5.00 ± 0.65 0.0496
  
1100         
 8 2.50 ± 0.91 0.5875
  
2200         
 8 4.75 ± 1.51 0.0683
Vehicle Control No Stressor 
 0         
 8 2.75 ± 0.92 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 01/09/90 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.6195
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
1         
 8 8.25 ± 1.33 0.0000
Test Chemical C.I. Acid orange 10 
550         
 8 1.25 ± 0.53 0.6193
  
1100         
 8 1.00 ± 0.53 0.7378
  
2200         
 8 1.25 ± 0.53 0.6193
Vehicle Control No Stressor 
 0         
 8 1.50 ± 0.50 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed