| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-01766-0011-0000-4 |
| Chemical Name: | C.I. Acid red 14 |
| CASRN: | 3567-69-9 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 142045_SCE |
| Study Result: | Positive |
Table Instructions and Notes:
Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 12/09/87 | 42 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 42 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Corn Oil | 0 | 4 | 7.14 ± 0.138 | |
| Test Chemical | C.I. Acid red 14 | 450 | 4 | 6.53 ± 0.880 | |
900 | 4 | 8.41 ± 0.774 | |||
1800 | 4 | 11.31 ± 2.275 | |||
| Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 13.97 ± 0.535 | |
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 01/27/88 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Corn Oil | 0 | 4 | 4.87 ± 0.160 | |
| Test Chemical | C.I. Acid red 14 | 450 | 4 | 7.78 ± 0.930 | |
900 | 4 | 6.69 ± 0.610 | |||
1800 | 4 | 9.45 ± 1.119 | |||
| Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 9.03 ± 0.784 | |
Footnotes: IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed