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Study Information
Study Attribute Value
CEBS Accession Number: 002-01771-0003-0000-1
Chemical Name: C.I. Basic red 9 monohydrochloride
CASRN: 569-61-9
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 724892_CA
Study Result: Negative

Study Result: Negative
Activation Trial Trial Call
No Activation  1  Negative 
Induced Rat Liver S9  1_S9  Negative 

Trial #:1   Activation: No Activation    Date: 08/10/1983    Harvest Time: 24 hour(s)   Trial Call: Negative   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Negative (Not Specified) 
0         
 100 1 0.010 1.0 1 0.010 1.0 0 0.000 0.0 0 0.000 0.0
Dimethyl Sulfoxide 
0         
 100 4 0.040 4.0 2 0.020 2.0 1 0.010 1.0 1 0.010 1.0
Test Chemical: C.I. Basic red 9 monohydrochloride 
10         
 100 6 0.060 5.0 4 0.040 3.0 1 0.010 1.0 1 0.010 1.0 
12.5       
 79 5 0.063 6.3 4 0.051 5.0 0 0.000 0.0 1 0.013 1.0 
15         
 100 5 0.050 4.0 0 0.000 0.0 2 0.020 2.0 3 0.030 2.0 
17.5       
 0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
Positive Control: Mitomycin-C 
 0.08      
 25 18 0.720 56.0 12 0.480 40.0 6 0.240 20.0 0 0.000 0.0
Trend: 0.118 -0.630 0.457  
Probability: 0.453 0.736 0.324  


Trial #:1_S9   Activation: Induced Rat Liver S9    Date: 08/10/1983    Harvest Time: 24 hour(s)   Trial Call: Negative   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Negative (Not Specified) 
0         
 100 1 0.010 1.0 1 0.010 1.0 0 0.000 0.0 0 0.000 0.0
Dimethyl Sulfoxide 
0         
 100 4 0.040 3.0 2 0.020 2.0 2 0.020 1.0 0 0.000 0.0
Test Chemical: C.I. Basic red 9 monohydrochloride 
40         
 100 3 0.030 3.0 1 0.010 1.0 1 0.010 1.0 1 0.010 1.0 
45         
 100 1 0.010 1.0 1 0.010 1.0 0 0.000 0.0 0 0.000 0.0 
50         
 100 6 0.060 5.0 2 0.020 2.0 3 0.030 2.0 1 0.010 1.0
Positive Control: Cyclophosphamide 
17.5       
 50 19 0.380 32.0 11 0.220 20.0 7 0.140 14.0 1 0.020 2.0
Trend: 0.492 -0.010 0.422  
Probability: 0.311 0.504 0.337