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Study Information
Study Attribute Value
CEBS Accession Number: 002-01796-0013-0000-9
Chemical Name: C.I. Disperse yellow 3
CASRN: 2832-40-8
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 221078_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 05/14/89 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.1955
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
25         
 8 14.25 ± 2.46 0.0000
Test Chemical C.I. Disperse yellow 3 
450         
 8 3.00 ± 1.00 0.1825
  
900         
 8 5.00 ± 1.41 0.0105
  
1800         
 8 3.00 ± 1.56 0.1825
Vehicle Control No Stressor 
 0         
 8 2.00 ± 0.65 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 06/27/89 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.4634
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 8.50 ± 0.98 0.0000
Test Chemical C.I. Disperse yellow 3 
450         
 8 1.25 ± 0.53 0.7196
  
900         
 8 3.25 ± 1.13 0.0871
  
1800         
 8 1.50 ± 0.33 0.6101
Vehicle Control No Stressor 
 0         
 8 1.75 ± 0.59 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed