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Study Information
Study Attribute Value
CEBS Accession Number: 002-01824-0011-0000-9
Chemical Name: Caprolactam
CASRN: 105-60-2
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 201538_SCE
Study Result: Negative (Nonstandard Protocol)


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 03/14/84 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 4.61 ± 0.475
Test Chemical Caprolactam 
175         
 4 4.38 ± 0.116
  
350         
 4 4.50 ± 0.292
  
700         
 4 4.41 ± 0.362
Positive Control Dimethylbenzanthracene 
5         
 4 10.64 ± 0.557


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed