| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-01845-0006-0000-6 |
| Chemical Name: | Chemical mixture - drinking water contaminants |
| CASRN: | CHEMMIXH2O |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | A18666_SCE |
| Study Result: | Negative (Nonstandard Protocol) |
Table Instructions and Notes:
Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 11/24/87 | 24 | Mouse | Female | B6C3F1 | Bone Marrow | Dosed-Water x 1, 14 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Water | 0 | 8 | 7.20 ± 0.452 | |
| Test Chemical | Chemical mixture - drinking water contaminants | 10 | 8 | 7.52 ± 0.579 | |
100 | 8 | 5.97 ± 0.594 | |||
200 | 8 | 9.21 ± 1.285 | |||
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 11/25/87 | 24 | Mouse | Male | B6C3F1 | Bone Marrow | Dosed-Water x 1, 14 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Water | 0 | 8 | 4.72 ± 0.224 | |
| Test Chemical | Chemical mixture - drinking water contaminants | 10 | 8 | 5.66 ± 0.246 | |
100 | 8 | 5.89 ± 0.333 | |||
200 | 8 | 5.36 ± 0.395 | |||
Footnotes: IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed