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Study Information
Study Attribute Value
CEBS Accession Number: 002-01845-0006-0000-6
Chemical Name: Chemical mixture - drinking water contaminants
CASRN: CHEMMIXH2O
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: A18666_SCE
Study Result: Negative (Nonstandard Protocol)


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 11/24/87 24 Mouse Female B6C3F1 Bone Marrow Dosed-Water x 1,  14 hour
  Dose
(mg/kg)
n SCE / Cell
(Mean ± SEM)
Pairwise P
Vehicle Control Water
 0         
8 7.20 ± 0.452
Test Chemical Chemical mixture - drinking water contaminants
10         
8 7.52 ± 0.579
 
100         
8 5.97 ± 0.594
 
200         
8 9.21 ± 1.285


Summary of Sister Chromatid Exchange Data (Trial 2)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 11/25/87 24 Mouse Male B6C3F1 Bone Marrow Dosed-Water x 1,  14 hour
  Dose
(mg/kg)
n SCE / Cell
(Mean ± SEM)
Pairwise P
Vehicle Control Water
 0         
8 4.72 ± 0.224
Test Chemical Chemical mixture - drinking water contaminants
10         
8 5.66 ± 0.246
 
100         
8 5.89 ± 0.333
 
200         
8 5.36 ± 0.395


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed