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Study Information
Study Attribute Value
CEBS Accession Number: 002-01865-0015-0000-8
Chemical Name: Chlorodibromomethane
CASRN: 124-48-1
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 687058_SCE
Study Result: Negative


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 07/29/86 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 4.66 ± 0.478
Test Chemical Chlorodibromomethane 
125         
 4 3.81 ± 0.219
  
250         
 4 3.48 ± 0.336
  
500         
 4 3.97 ± 0.326
Positive Control Dimethylbenzanthracene 
2.5       
 4 8.74 ± 0.470


Summary of Sister Chromatid Exchange Data (Trial 2)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 02/06/89 42 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  42 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 4.17 ± 0.557
Test Chemical Chlorodibromomethane 
100         
 4 4.17 ± 0.221
  
200         
 4 6.09 ± 1.146
  
400         
 4 4.40 ± 0.528
Positive Control Dimethylbenzanthracene 
2.5       
 4 8.59 ± 1.064


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed