| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-01865-0015-0000-8 |
| Chemical Name: | Chlorodibromomethane |
| CASRN: | 124-48-1 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 687058_SCE |
| Study Result: | Negative |
Table Instructions and Notes:
Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 07/29/86 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Corn Oil | 0 | 4 | 4.66 ± 0.478 | |
| Test Chemical | Chlorodibromomethane | 125 | 4 | 3.81 ± 0.219 | |
250 | 4 | 3.48 ± 0.336 | |||
500 | 4 | 3.97 ± 0.326 | |||
| Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 8.74 ± 0.470 | |
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 02/06/89 | 42 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 42 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Corn Oil | 0 | 4 | 4.17 ± 0.557 | |
| Test Chemical | Chlorodibromomethane | 100 | 4 | 4.17 ± 0.221 | |
200 | 4 | 6.09 ± 1.146 | |||
400 | 4 | 4.40 ± 0.528 | |||
| Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 8.59 ± 1.064 | |
Footnotes: IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed