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Study Information
Study Attribute Value
CEBS Accession Number: 002-01934-0011-0000-1
Chemical Name: Cytembena
CASRN: 21739-91-3
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 483291_SCE
Study Result: Negative (Nonstandard Protocol)


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 01/22/91 24 Mouse Male B6C3F1 Bone Marrow subcutaneously implanted x 1,  24 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Phosphate Buffered Saline 
 0         
 4 2.92 ± 0.355
Test Chemical Cytembena 
25         
 3 3.44 ± 0.586
  
50         
 4 3.20 ± 0.467
  
100         
 4 3.43 ± 0.415
Positive Control Mitomycin-C 
 0.5       
 4 6.14 ± 0.353


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed