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Study Information
Study Attribute Value
CEBS Accession Number: 002-01940-0011-0000-8
Chemical Name: D & C red no. 9
CASRN: 5160-02-1
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 832755_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 08/09/88 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.8728
Test Group Dose
(mg/kg)
n Percent Cells w/ Aberrations
(Mean ± SEM)
Pairwise P
Positive Control Dimethylbenzanthracene
50         
8 17.00 ± 2.10 0.0000
Test Chemical D & C red no. 9
1250         
8 2.25 ± 0.59 0.6747
 
2500         
8 2.50 ± 0.82 0.5875
 
5000         
8 1.50 ± 0.50 0.8899
Vehicle Control No Stressor
 0         
8 2.75 ± 0.75 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 08/22/88 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0626
Test Group Dose
(mg/kg)
n Percent Cells w/ Aberrations
(Mean ± SEM)
Pairwise P
Positive Control Dimethylbenzanthracene
100         
8 14.00 ± 2.80 0.0000
Test Chemical D & C red no. 9
1250         
8 1.25 ± 0.75 0.3687
 
2500         
8 1.75 ± 0.59 0.1812
 
5000         
8 2.25 ± 0.59 0.0810
Vehicle Control No Stressor
 0         
8 1.00 ± 0.53 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed