Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-01984-0013-0000-8 |
Chemical Name: | Diallyl phthalate |
CASRN: | 131-17-9 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | 993263_SCE |
Study Result: | Positive |
Table Instructions and Notes:
Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.
Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|---|
SCE | 12/10/87 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
---|---|---|---|---|---|
Vehicle Control | Corn Oil | 0 | 4 | 4.25 ± 0.567 | |
Test Chemical | Diallyl phthalate | 75 | 4 | 4.80 ± 0.613 | |
150 | 4 | 5.51 ± 0.246 | |||
300 | 4 | 7.06 ± 0.649 | |||
Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 8.81 ± 1.149 |
Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|---|
SCE | 07/06/88 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
---|---|---|---|---|---|
Vehicle Control | Corn Oil | 0 | 4 | 4.50 ± 0.071 | |
Test Chemical | Diallyl phthalate | 225 | 4 | 7.14 ± 1.289 | |
300 | 3 | 7.36 ± 0.793 | |||
Positive Control | Dimethylbenzanthracene | 2.5 | 4 | 7.10 ± 0.466 |
Footnotes: IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed