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Study Information
Study Attribute Value
CEBS Accession Number: 002-01984-0013-0000-8
Chemical Name: Diallyl phthalate
CASRN: 131-17-9
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 993263_SCE
Study Result: Positive


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 12/10/87 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 4.25 ± 0.567
Test Chemical Diallyl phthalate 
75         
 4 4.80 ± 0.613
  
150         
 4 5.51 ± 0.246
  
300         
 4 7.06 ± 0.649
Positive Control Dimethylbenzanthracene 
2.5       
 4 8.81 ± 1.149


Summary of Sister Chromatid Exchange Data (Trial 2)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 07/06/88 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Corn Oil 
 0         
 4 4.50 ± 0.071
Test Chemical Diallyl phthalate 
225         
 4 7.14 ± 1.289
  
300         
 3 7.36 ± 0.793
Positive Control Dimethylbenzanthracene 
2.5       
 4 7.10 ± 0.466


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed