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Study Information
Study Attribute Value
CEBS Accession Number: 002-01984-0014-0000-9
Chemical Name: Diallyl phthalate
CASRN: 131-17-9
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 993263_CA
Study Result: Positive

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 11/28/88 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0149
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 14.25 ± 2.09 0.0000
Test Chemical Diallyl phthalate 
75         
 8 6.50 ± 1.18 0.0164
  
150         
 8 2.75 ± 0.84 0.6608
  
300         
 8 7.50 ± 1.18 0.0038
Vehicle Control No Stressor 
 0         
 8 3.25 ± 1.25 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 08/28/89 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0114
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
50         
 8 11.50 ± 1.68 0.0000
Test Chemical Diallyl phthalate 
75         
 8 2.25 ± 0.80 0.1404
  
150         
 8 2.00 ± 0.76 0.2008
  
300         
 8 3.75 ± 0.96 0.0118
Vehicle Control No Stressor 
 0         
 8 1.25 ± 0.37 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed