COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
Study Information
Study Attribute Value
CEBS Accession Number: 002-02013-0015-0000-4
Chemical Name: Dichlorvos
CASRN: 62-73-7
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 755734_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 07/15/83 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.6161
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Test Chemical Dichlorvos 
6.25      
 8 0.75 ± 0.53 0.9749
  
12.5       
 8 1.75 ± 0.45 0.7690
  
25         
 8 1.75 ± 0.70 0.7690
Vehicle Control No Stressor 
 0         
 8 2.50 ± 0.63 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 03/09/88 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.1112
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
1         
 8 8.00 ± 1.51 0.0000
Test Chemical Dichlorvos 
3.2       
 8 0.75 ± 0.53 0.5000
  
6.5       
 8 2.00 ± 0.76 0.0645
  
13         
 8 1.50 ± 0.50 0.1573
Vehicle Control No Stressor 
 0         
 8 0.75 ± 0.53 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed