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Study Information
Study Attribute Value
CEBS Accession Number: 002-02044-0015-0000-8
Chemical Name: Diglycidyl resorcinol ether (DGRE)
CASRN: 101-90-6
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 389996_SCE
Study Result: Positive


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 01/29/86 17 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  17 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Dimethyl Sulfoxide 
 0         
 4 4.21 ± 0.508
Test Chemical Diglycidyl resorcinol ether (DGRE) 
62.5       
 4 4.46 ± 0.457
  
125         
 4 4.61 ± 0.710
  
250         
 4 7.59 ± 0.671
Positive Control Dimethylbenzanthracene 
100         
 4 11.63 ± 0.647


Summary of Sister Chromatid Exchange Data (Trial 2)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 02/06/86 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Dimethyl Sulfoxide 
 0         
 4 4.25 ± 0.398
Test Chemical Diglycidyl resorcinol ether (DGRE) 
62.5       
 4 5.72 ± 0.613
  
125         
 4 7.57 ± 0.733
  
250         
 4 16.75 ± 2.149
Positive Control Dimethylbenzanthracene 
2.5       
 4 7.82 ± 0.612


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed