Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02044-0018-0000-1 |
Chemical Name: | Diglycidyl resorcinol ether (DGRE) |
CASRN: | 101-90-6 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | 873378_CA |
Study Result: | Positive (Nonstandard Protocol) |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 08/21/86 | 17 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 17 hour | 0.0000 |
Test Group | Dose (mg/kg) | n | Percent Cells w/ Aberrations (Mean ± SEM) | Pairwise P | |
---|---|---|---|---|---|
Positive Control | Dimethylbenzanthracene | 100 | 8 | 7.75 ± 1.58 | 0.0000 |
Test Chemical | Diglycidyl resorcinol ether (DGRE) | 150 | 8 | 1.50 ± 0.73 | 0.5000 |
300 | 8 | 2.00 ± 0.53 | 0.2949 | ||
600 | 8 | 9.00 ± 2.62 | 0.0000 | ||
Vehicle Control | No Stressor | 0 | 8 | 1.50 ± 0.50 | 0.0000 |
Footnotes: IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed
INHAL: Inhalation
n: Number of animals analyzed