Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02064-0012-0000-7 |
Chemical Name: | Dimethyl morpholinophosphoramidate |
CASRN: | 597-25-1 |
NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
NTP Study ID: | 963455_CA |
Study Result: | Negative (Nonstandard Protocol) |
Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
---|---|---|---|---|---|---|---|
CA | 08/22/89 | 17 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 17 hour | 0.6864 |
Test Group | Dose (mg/kg) | n | Percent Cells w/ Aberrations (Mean ± SEM) | Pairwise P | |
---|---|---|---|---|---|
Positive Control | Mitomycin-C | 1 | 8 | 11.25 ± 1.36 | 0.0000 |
Test Chemical | Dimethyl morpholinophosphoramidate | 2000 | 8 | 2.00 ± 0.65 | 0.6832 |
4000 | 8 | 2.00 ± 0.38 | 0.6832 | ||
Vehicle Control | No Stressor | 0 | 8 | 2.50 ± 0.91 | 0.0000 |
Footnotes: IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed
INHAL: Inhalation
n: Number of animals analyzed