COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
Study Information
Study Attribute Value
CEBS Accession Number: 002-02084-0013-0000-0
Chemical Name: Dimethylvinyl chloride (DMVC)
CASRN: 513-37-1
NTP Study Type: Genetic Toxicology - Drosophila Germ Cell Mutagenicity
NTP Study ID: 758308_SLRL
Study Result: Positive

Table Instructions and Notes:

In some Drosophila SLRL studies, clusters (mutations concluded to result from a single spontaneous pre-meiotic event) in a single male were identified and all the data from that male were excluded from the study analysis. The published reports of these data present the adjusted values. The SLRL data on this web site are uncorrected for the removal of clusters. However, the overall conclusion of the study matches the published conclusion. If you require access to the corrected data, please refer to the associated journal or contact the NTP for a copy of the printed report.


You may also view: Reciprocal Translocations Data for this study.


Drosophilia Sex-Linked Recessive Lethal Study Details
Route of
Exposure
Dose
(ppm)
Percent
Mortality
Percent
Sterility
No. of Lethals / No. of X Chromosomes Tested Total Lethals / Total Tests Cluster Removed
Mating 1 Mating 2 Mating 3
Test Chemical
12750         
22 11 9/3161 19/2960 10/2274 38/8395 (0.45%) Y
Vehicle Control
 0         
3/2922 6/2916 5/2570 14/8408 (0.17%) N
  P= 0.002
Abbreviations:
Br = Brood