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Study Information
Study Attribute Value
CEBS Accession Number: 002-02132-0001-0000-1
Chemical Name: Ethoxylated dodecyl alcohol
CASRN: 9002-92-0
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 000181_SCE
Study Result: Negative

Study Result: Negative
Activation Trial Trial Call
No Activation  1   
Induced Rat Liver S9  1_S9   

Trial #: 1    Activation: No Activation    Date: 06/11/1985    Trial Call:   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Medium 
0         
 50 1047 383 0.366 7.66 26.5 0.000
Test Chemical Ethoxylated dodecyl alcohol 
 0.306     
 50 1044 371 0.355 7.42 26.5 -2.855 
1.02      
 50 1042 373 0.358 7.46 26.5 -2.144 
3.06      
 50 1043 379 0.363 7.58 26.5 -0.665
Positive Control Mitomycin-C 
 0.0015    
 50 1047 621 0.593 12.42 26.5 62.141
Mitomycin-C 
 0.01      
 10 208 332 1.596 33.20 26.5 336.338
Trend: -0.060        
Probability: 0.524        

Trial #: 1_S9    Activation: Induced Rat Liver S9    Date: 06/11/1985    Trial Call:   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Medium 
0         
 50 1043 465 0.446 9.30 26.0 0.000
Test Chemical Ethoxylated dodecyl alcohol 
3.06      
 50 1044 421 0.403 8.42 26.0 -9.549 
10.2       
 50 1050 455 0.433 9.10 26.0 -2.803 
30.6       
 50 1050 449 0.428 8.98 26.0 -4.085
Positive Control Cyclophosphamide 
 0.4       
 50 1048 745 0.711 14.90 26.0 59.451
Cyclophosphamide 
2.5       
 10 208 403 1.938 40.30 26.0 334.583
Trend: -0.263        
Probability: 0.604