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Study Information
Study Attribute Value
CEBS Accession Number: 002-02132-0002-0000-2
Chemical Name: Ethoxylated dodecyl alcohol
CASRN: 9002-92-0
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 000181_CA
Study Result: Negative

Study Result: Negative
Activation Trial Trial Call
No Activation  Negative 
Induced Rat Liver S9  1_S9  Negative 

Trial #:1   Activation: No Activation    Date: 07/25/1985    Harvest Time: 10.5 hour(s)   Trial Call: Negative   
  Dose
µg/mL
Total
Cells Examined
Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
Vehicle Control: Medium
0         
100 4 0.040 2.0 0 0.000 0.0 4 0.040 2.0 0 0.000 0.0
Test Chemical: Ethoxylated dodecyl alcohol
5         
100 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
15         
100 2 0.020 2.0 0 0.000 0.0 2 0.020 2.0 0 0.000 0.0
50         
100 2 0.020 2.0 0 0.000 0.0 2 0.020 2.0 0 0.000 0.0
Positive Control: Mitomycin-C
1         
100 22 0.220 20.0 7 0.070 7.0 15 0.150 15.0 0 0.000 0.0
Mitomycin-C
5         
50 23 0.460 36.0 5 0.100 10.0 18 0.360 28.0 0 0.000 0.0
Trend: 0.361 0.000 0.361  
Probability: 0.359 0.000 0.359  


Trial #:1_S9   Activation: Induced Rat Liver S9    Date: 07/25/1985    Harvest Time: 12 hour(s)   Trial Call: Negative   
  Dose
µg/mL
Total
Cells Examined
Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
No. of
Abs.
Abs
Per
Cell
% Cells
With
Abs
Vehicle Control: Medium
0         
100 1 0.010 1.0 0 0.000 0.0 1 0.010 1.0 0 0.000 0.0
Test Chemical: Ethoxylated dodecyl alcohol
5         
100 1 0.010 1.0 0 0.000 0.0 1 0.010 1.0 0 0.000 0.0
15         
100 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
50         
100 2 0.020 2.0 0 0.000 0.0 2 0.020 2.0 0 0.000 0.0
Positive Control: Cyclophosphamide
50         
50 28 0.560 34.0 12 0.240 16.0 16 0.320 26.0 0 0.000 0.0
Trend: 0.472 0.000 0.472  
Probability: 0.318 0.000 0.318