Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02132-0002-0000-2 |
Chemical Name: | Ethoxylated dodecyl alcohol |
CASRN: | 9002-92-0 |
NTP Study Type: | Genetic Toxicology - Mammalian Cell Cytogenetics |
NTP Study ID: | 000181_CA |
Study Result: | Negative |
Activation | Trial | Trial Call |
---|---|---|
No Activation | 1 | Negative |
Induced Rat Liver S9 | 1_S9 | Negative |
Dose µg/mL | Total Cells Examined | Total Aberrations | Complex Aberrations | Simple Aberrations | Other Abs | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
No. of Abs | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | ||||
Vehicle Control: | Medium | 0 | 100 | 4 | 0.040 | 2.0 | 0 | 0.000 | 0.0 | 4 | 0.040 | 2.0 | 0 | 0.000 | 0.0 |
Test Chemical: | Ethoxylated dodecyl alcohol | 5 | 100 | 0 | 0.000 | 0.0 | 0 | 0.000 | 0.0 | 0 | 0.000 | 0.0 | 0 | 0.000 | 0.0 |
15 | 100 | 2 | 0.020 | 2.0 | 0 | 0.000 | 0.0 | 2 | 0.020 | 2.0 | 0 | 0.000 | 0.0 | ||
50 | 100 | 2 | 0.020 | 2.0 | 0 | 0.000 | 0.0 | 2 | 0.020 | 2.0 | 0 | 0.000 | 0.0 | ||
Positive Control: | Mitomycin-C | 1 | 100 | 22 | 0.220 | 20.0 | 7 | 0.070 | 7.0 | 15 | 0.150 | 15.0 | 0 | 0.000 | 0.0 |
Mitomycin-C | 5 | 50 | 23 | 0.460 | 36.0 | 5 | 0.100 | 10.0 | 18 | 0.360 | 28.0 | 0 | 0.000 | 0.0 | |
Trend: | 0.361 | 0.000 | 0.361 | ||||||||||||
Probability: | 0.359 | 0.000 | 0.359 |
Dose µg/mL | Total Cells Examined | Total Aberrations | Complex Aberrations | Simple Aberrations | Other Abs | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
No. of Abs | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | No. of Abs. | Abs Per Cell | % Cells With Abs | ||||
Vehicle Control: | Medium | 0 | 100 | 1 | 0.010 | 1.0 | 0 | 0.000 | 0.0 | 1 | 0.010 | 1.0 | 0 | 0.000 | 0.0 |
Test Chemical: | Ethoxylated dodecyl alcohol | 5 | 100 | 1 | 0.010 | 1.0 | 0 | 0.000 | 0.0 | 1 | 0.010 | 1.0 | 0 | 0.000 | 0.0 |
15 | 100 | 0 | 0.000 | 0.0 | 0 | 0.000 | 0.0 | 0 | 0.000 | 0.0 | 0 | 0.000 | 0.0 | ||
50 | 100 | 2 | 0.020 | 2.0 | 0 | 0.000 | 0.0 | 2 | 0.020 | 2.0 | 0 | 0.000 | 0.0 | ||
Positive Control: | Cyclophosphamide | 50 | 50 | 28 | 0.560 | 34.0 | 12 | 0.240 | 16.0 | 16 | 0.320 | 26.0 | 0 | 0.000 | 0.0 |
Trend: | 0.472 | 0.000 | 0.472 | ||||||||||||
Probability: | 0.318 | 0.000 | 0.318 |