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Study Information
Study Attribute Value
CEBS Accession Number: 002-02132-0003-0000-3
Chemical Name: Ethoxylated dodecyl alcohol
CASRN: 9002-92-0
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 487120_SCE
Study Result: Negative

Study Result: Negative
Activation Trial Trial Call
No Activation  1  Negative 
Induced Rat Liver S9  1_S9  Negative 

Trial #: 1    Activation: No Activation    Date: 02/24/1987    Trial Call: Negative   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Negative (Not Specified) 
0         
 50 1051 363 0.345 7.26 26.0 0.000
Test Chemical Ethoxylated dodecyl alcohol 
 0.16      
 50 1047 385 0.368 7.70 26.0 6.466 
 0.5       
 50 1050 404 0.385 8.08 26.0 11.401 
1.6       
 50 1050 397 0.378 7.94 26.0 9.471 
5         
 0 0 0 0.000 0.00 26.0 N/A
Positive Control Mitomycin-C 
 0.0E-4    
 50 1049 507 0.483 10.14 26.0 39.936
Mitomycin-C 
 0.005     
 10 210 266 1.267 26.60 26.0 266.740
Trend: 1.371        
Probability: 0.085        

Trial #: 1_S9    Activation: Induced Rat Liver S9    Date: 02/24/1987    Trial Call: Negative   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Negative (Not Specified) 
0         
 50 1045 451 0.432 9.02 26.0 0.000
Test Chemical Ethoxylated dodecyl alcohol 
 0.5       
 50 1048 405 0.386 8.10 26.0 -10.457 
1.6       
 50 1050 443 0.422 8.86 26.0 -2.242 
5         
 50 1050 472 0.450 9.44 26.0 4.158 
16         
 50 1044 453 0.434 9.06 26.0 0.540
Positive Control Cyclophosphamide 
 0.15      
 50 1050 556 0.530 11.12 26.0 22.695
Cyclophosphamide 
 0.6       
 10 210 240 1.143 24.00 26.0 164.808
Trend: 1.063        
Probability: 0.144