| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02132-0009-0000-9 |
| Chemical Name: | Ethoxylated dodecyl alcohol |
| CASRN: | 9002-92-0 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 844342_SCE |
| Study Result: | Negative (Nonstandard Protocol) |
Table Instructions and Notes:
Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 01/22/91 | 24 | Mouse | Male | B6C3F1 | Bone Marrow | subcutaneously implanted x 1, 24 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Phosphate Buffered Saline | 0 | 4 | 2.92 ± 0.355 | |
| Test Chemical | Ethoxylated dodecyl alcohol | 50 | 4 | 2.55 ± 0.271 | |
100 | 4 | 3.63 ± 0.585 | |||
200 | 4 | 4.03 ± 0.950 | |||
| Positive Control | Mitomycin-C | 0.5 | 4 | 6.14 ± 0.353 | |
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 05/24/89 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
| Dose (mg/kg) | n | SCE / Cell (Mean ± SEM) | Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Phosphate Buffered Saline | 0 | 4 | 4.68 ± 0.918 | |
| Test Chemical | Ethoxylated dodecyl alcohol | 50 | 4 | 5.23 ± 0.837 | |
100 | 4 | 4.08 ± 0.433 | |||
200 | 4 | 7.52 ± 1.947 | |||
| Positive Control | Mitomycin-C | 0.5 | 4 | 7.46 ± 0.508 | |
Footnotes: IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed