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Study Information
Study Attribute Value
CEBS Accession Number: 002-02132-0010-0000-1
Chemical Name: Ethoxylated dodecyl alcohol
CASRN: 9002-92-0
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 844342_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 06/04/91 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0640
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
1         
 8 9.75 ± 3.01 0.0000
Test Chemical Ethoxylated dodecyl alcohol 
62.5       
 8 0.75 ± 0.37 0.6479
  
125         
 8 1.50 ± 0.82 0.2622
  
250         
 8 2.00 ± 0.65 0.1223
Vehicle Control No Stressor 
 0         
 8 1.00 ± 0.53 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 09/23/92 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.0152
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
1         
 8 9.00 ± 2.51 0.0000
Test Chemical Ethoxylated dodecyl alcohol 
37.5       
 8 0.25 ± 0.25 0.8420
  
75         
 8 1.50 ± 0.63 0.1573
  
150         
 8 2.00 ± 0.65 0.0645
Vehicle Control No Stressor 
 0         
 8 0.75 ± 0.37 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 03/30/93 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.0552
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Mitomycin-C 
1         
 8 15.75 ± 1.62 0.0000
Test Chemical Ethoxylated dodecyl alcohol 
75         
 8 1.25 ± 0.75 0.1274
  
112.5       
 8 2.00 ± 0.85 0.0281
  
150         
 8 1.50 ± 0.82 0.0776
Vehicle Control No Stressor 
 0         
 8 0.50 ± 0.50 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed