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Study Information
Study Attribute Value
CEBS Accession Number: 002-02132-0010-0000-1
Chemical Name: Ethoxylated dodecyl alcohol
CASRN: 9002-92-0
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 844342_CA
Study Result: Negative

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 06/04/91 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0640
Test Group Dose
(mg/kg)
n Percent Cells w/ Aberrations
(Mean ± SEM)
Pairwise P
Positive Control Mitomycin-C
1         
8 9.75 ± 3.01 0.0000
Test Chemical Ethoxylated dodecyl alcohol
62.5       
8 0.75 ± 0.37 0.6479
 
125         
8 1.50 ± 0.82 0.2622
 
250         
8 2.00 ± 0.65 0.1223
Vehicle Control No Stressor
 0         
8 1.00 ± 0.53 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 09/23/92 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.0152
Test Group Dose
(mg/kg)
n Percent Cells w/ Aberrations
(Mean ± SEM)
Pairwise P
Positive Control Mitomycin-C
1         
8 9.00 ± 2.51 0.0000
Test Chemical Ethoxylated dodecyl alcohol
37.5       
8 0.25 ± 0.25 0.8420
 
75         
8 1.50 ± 0.63 0.1573
 
150         
8 2.00 ± 0.65 0.0645
Vehicle Control No Stressor
 0         
8 0.75 ± 0.37 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 03/30/93 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.0552
Test Group Dose
(mg/kg)
n Percent Cells w/ Aberrations
(Mean ± SEM)
Pairwise P
Positive Control Mitomycin-C
1         
8 15.75 ± 1.62 0.0000
Test Chemical Ethoxylated dodecyl alcohol
75         
8 1.25 ± 0.75 0.1274
 
112.5       
8 2.00 ± 0.85 0.0281
 
150         
8 1.50 ± 0.82 0.0776
Vehicle Control No Stressor
 0         
8 0.50 ± 0.50 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed