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Study Information
Study Attribute Value
CEBS Accession Number: 002-02148-0009-0000-6
Chemical Name: Ethyl methanesulfonate
CASRN: 62-50-0
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 998123_CA
Study Result: Positive (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 06/09/83 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.0006
Test Group Dose
(mg/kg)
n Percent Cells w/ Aberrations
(Mean ± SEM)
Pairwise P
Test Chemical Ethyl methanesulfonate
93.75      
4 5.00 ± 0.71 0.0187
 
187.5       
4 6.50 ± 0.87 0.0016
 
375         
4 7.50 ± 1.50 0.0003
Vehicle Control No Stressor
 0         
4 2.25 ± 0.95 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed