| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02148-0009-0000-6 |
| Chemical Name: | Ethyl methanesulfonate |
| CASRN: | 62-50-0 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 998123_CA |
| Study Result: | Positive (Nonstandard Protocol) |
| Test Type | Start Date | Sample Time (h) | Species | Sex | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|
| CA | 06/09/83 | 17 | Mouse | Male | Bone Marrow | Intraperitoneal Injection x 1/study, 17 hour | 0.0006 |
| Test Group | Dose (mg/kg) | n | Percent Cells w/ Aberrations (Mean ± SEM) | Pairwise P | |
|---|---|---|---|---|---|
| Test Chemical | Ethyl methanesulfonate | 93.75 | 4 | 5.00 ± 0.71 | 0.0187 |
187.5 | 4 | 6.50 ± 0.87 | 0.0016 | ||
375 | 4 | 7.50 ± 1.50 | 0.0003 | ||
| Vehicle Control | No Stressor | 0 | 4 | 2.25 ± 0.95 | 0.0000 |
Footnotes: IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed
INHAL: Inhalation
n: Number of animals analyzed