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Study Information
Study Attribute Value
CEBS Accession Number: 002-02150-0001-0000-1
Chemical Name: Ethyl tellurac
CASRN: 20941-65-5
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 274642_SCE
Study Result: Negative

Study Result: Negative
Activation Trial Trial Call
No Activation  1  Negative 
Induced Rat Liver S9  1_S9  Negative 

Trial #: 1    Activation: No Activation    Date: 05/05/1983    Trial Call: Negative   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Dimethyl Sulfoxide 
0         
 50 1049 399 0.380 7.98 26.0 0.000
Test Chemical Ethyl tellurac 
 0.01      
 50 1047 464 0.443 9.28 26.0 16.513 
 0.015     
 50 1050 473 0.450 9.46 26.0 18.433 
 0.02      
 50 1043 461 0.442 9.22 26.0 16.204
Positive Control Mitomycin-C 
 0.005     
 25 524 735 1.403 29.40 26.0 268.773
Trend: 2.166        
Probability: 0.015        

Trial #: 1_S9    Activation: Induced Rat Liver S9    Date: 03/16/1983    Trial Call: Negative   
  Dose
µg/mL		 Number
Cells
Examined		 Number
Chromosomes
Examined		 Total
Number
SCEs		 SCE /
Chromosome		 SCE /
Cell		 Hours in
BRDU		 % Increase
Over Solvent
Control
Vehicle Control Dimethyl Sulfoxide 
0         
 50 1047 465 0.444 9.30 26.0 0.000
Test Chemical Ethyl tellurac 
 0.1       
 50 1047 455 0.435 9.10 26.0 -2.151 
 0.32      
 50 1050 486 0.463 9.72 26.0 4.218 
1         
 50 1048 477 0.455 9.54 26.0 2.483
Positive Control Cyclophosphamide 
1         
 50 1047 873 0.834 17.46 26.0 87.742
Trend: 0.665        
Probability: 0.253