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Study Information
Study Attribute Value
CEBS Accession Number: 002-02150-0002-0000-2
Chemical Name: Ethyl tellurac
CASRN: 20941-65-5
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 274642_CA
Study Result: Equivocal

Study Result: Equivocal
Activation Trial Trial Call
No Activation  1  Positive 
Induced Rat Liver S9  1_S9  Negative 

Trial #:1   Activation: No Activation    Date: 03/16/1983    Harvest Time: 14 hour(s)   Trial Call: Positive   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Dimethyl Sulfoxide 
0         
 100 3 0.030 3.0 0 0.000 0.0 3 0.030 3.0 0 0.000 0.0
Test Chemical: Ethyl tellurac 
 0.032     
 100 10 0.100 8.0 2 0.020 2.0 8 0.080 6.0 0 0.000 0.0 
 0.1       
 100 26 0.260 19.0 0 0.000 0.0 26 0.260 19.0 0 0.000 0.0 
 0.32      
 100 15 0.150 11.0 2 0.020 2.0 13 0.130 9.0 0 0.000 0.0
Positive Control: Mitomycin-C 
 0.15      
 100 42 0.420 29.0 14 0.140 11.0 28 0.280 22.0 0 0.000 0.0
Trend: 2.570 0.904 2.379  
Probability: 0.005 0.183 0.009  


Trial #:1_S9   Activation: Induced Rat Liver S9    Date: 03/16/1983    Harvest Time: 14 hour(s)   Trial Call: Negative   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Dimethyl Sulfoxide 
0         
 100 4 0.040 4.0 1 0.010 1.0 3 0.030 3.0 0 0.000 0.0
Test Chemical: Ethyl tellurac 
 0.1       
 100 4 0.040 3.0 1 0.010 1.0 3 0.030 2.0 0 0.000 0.0 
 0.32      
 100 6 0.060 6.0 2 0.020 2.0 4 0.040 4.0 0 0.000 0.0 
1         
 100 6 0.060 6.0 2 0.020 2.0 4 0.040 4.0 0 0.000 0.0
Positive Control: Cyclophosphamide 
15         
 50 19 0.380 30.0 7 0.140 14.0 12 0.240 20.0 0 0.000 0.0
Trend: 0.948 0.737 0.632  
Probability: 0.172 0.231 0.264