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Study Information
Study Attribute Value
CEBS Accession Number: 002-02171-0011-0000-5
Chemical Name: FD & C yellow no. 6
CASRN: 2783-94-0
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 848256_SCE
Study Result: Negative (Nonstandard Protocol)


Table Instructions and Notes:

Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.


Summary of Sister Chromatid Exchange Data (Trial 1)
Test Type Start Date Sample Time (h) Species Sex Strain Tissue Protocol Trend
Test P
SCE 10/12/87 23 Mouse Male B6C3F1 Bone Marrow IP/IJ x 1,  23 hour
  Dose
(mg/kg)		 n SCE / Cell
(Mean ± SEM)		 Pairwise P
Vehicle Control Phosphate Buffered Saline 
 0         
 4 3.90 ± 0.283
Test Chemical FD & C yellow no. 6 
1225         
 4 3.66 ± 0.025
  
2450         
 4 4.42 ± 0.307
  
4900         
 4 3.90 ± 0.375
Positive Control Mitomycin-C 
 0.5       
 4 6.28 ± 0.597


Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed