COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
Study Information
Study Attribute Value
CEBS Accession Number: 002-02194-0002-0000-0
Chemical Name: Furfural
CASRN: 98-01-1
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 384163_CA
Study Result: Positive

Study Result: Positive
Activation Trial Trial Call
No Activation  1  Positive 
Induced Rat Liver S9  1_S9  Weakly Positive* 

Trial #:1   Activation: No Activation    Date: 02/03/1983    Harvest Time: 23.5 hour(s)   Trial Call: Positive   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Negative (Not Specified) 
0         
 100 2 0.020 2.0 1 0.010 1.0 0 0.000 0.0 1 0.010 1.0
Dimethyl Sulfoxide 
0         
 100 3 0.030 3.0 2 0.020 2.0 0 0.000 0.0 1 0.010 1.0
Test Chemical: Furfural 
200         
 100 7 0.070 5.0 1 0.010 1.0 4 0.040 2.0 2 0.020 2.0 
300         
 100 7 0.070 6.0 0 0.000 0.0 7 0.070 6.0 0 0.000 0.0 
401         
 100 24 0.240 15.0 6 0.060 6.0 6 0.060 5.0 12 0.120 3.0 
501         
 100 23 0.230 22.0 13 0.130 13.0 10 0.100 9.0 0 0.000 0.0
Positive Control: Mitomycin-C 
 0.05      
 50 26 0.520 28.0 9 0.180 16.0 7 0.140 12.0 10 0.200 2.0
Trend: 4.854 3.885 3.239  
Probability: 0.000 0.000 0.001  


Trial #:1_S9   Activation: Induced Rat Liver S9    Date: 02/03/1983    Harvest Time: 22 hour(s)   Trial Call: Weakly Positive*   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Negative (Not Specified) 
0         
 100 4 0.040 4.0 2 0.020 2.0 1 0.010 1.0 1 0.010 1.0
Dimethyl Sulfoxide 
0         
 100 5 0.050 5.0 3 0.030 3.0 1 0.010 1.0 1 0.010 1.0
Test Chemical: Furfural 
500         
 100 4 0.040 4.0 1 0.010 1.0 1 0.010 1.0 2 0.020 2.0 
760         
 100 6 0.060 6.0 3 0.030 3.0 3 0.030 3.0 0 0.000 0.0 
1000         
 100 118 1.180 54.0 75 0.750 45.0 31 0.310 23.0 12 0.120 3.0 
1230         
 0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
Positive Control: Cyclophosphamide 
10         
 50 12 0.240 22.0 4 0.080 8.0 8 0.160 16.0 0 0.000 0.0
Trend: 8.486 8.190 5.767  
Probability: 0.000 0.000 0.000